InSitu Sterilizable Fermenter Bioreactor Lab Scale BioFMX

Model No : Fermex BioFMX

Capacity : 5L to 40L

Industry : Pharmaceutical & Biotech Industry, University, Research Institutes

BioFMX series is a range of In-situ fermenters for lab scale. They are available in standalone, twin, and parallel models.  Fermex In-situ fermenters and bioreactors are made up of high-quality SS316L material which is non-corrosive and non-toxic and provides the best sterile environment for microbial culture growth. BioFMX range starts from 5L to 40L and is available in various Automation modes (Basic, Semi, and Fully Automatic). Fermex is the best quality Bioreactors manufacturer in India, thus our Bioreactors are an asset for any research labs, universities, biotechnology, and biopharma industries.

Key Features

• In-situ Sterilization (SIP): Sterilization within the vessel, no transfer needed.

• Compact Design: Space-saving and easy to operate in labs.

• Capacity Range: 5–20 L working volume.

• Durable Build: SS316L contact parts with hygienic design.

• Efficient Agitation: Mechanical seal-based agitator with variable speed.

• Automated Controls: PLC/PID-based system for pH, DO, temp, foam & aeration.

• Sampling & Harvesting: Sterile access ports for ease of use.

• Data Integration: SCADA compatibility for monitoring & analysis.

• Safety Features: Protection against over-temperature and pressure.

Technical Specifications:

Type: Sterilization in Place (SIP) and Cleaning in Place (CIP)

Design Code: ASME BPE-2019

Temperature: 0 to 150 °C

pH: 2 to 14

DO2: 0-100%

MOC: SS 316L

Automation Grade: Manual, Semi Automatic& Fully Automatic

Surface Finish: Inner surface 420 grit mirror-finished Ra 0.25 to 0.5μm and External 120 to 180 grit matt finish

Features:

• Bottom or top driven agitator (Single/Double mechanical seal or Magnetic drive) with Rushton Turbine impellers.
• Automated control of process parameters like Aeration, Temperature, Foaming, Pressure, pH, DO, etc. Automatic aeration control through MFC for multiple gases also.
• Feed addition through precise flow controlled peristaltic pumps for accuracy of feeding.
• Specially designed Zero dead leg sampling valves and harvest valves.
• PLC-based panels are provided with a color touch screen HMI to provide the operator with monitoring and control of various parameters.
• Mobile App/web server is provided for data monitoring purposes.
• Alarms SMS alert on mobile is provided.
• Reserve data logging with SCADA software is also provided so that no important data of the batch is lost out.
• All wet parts are made of SS316/316L and non-wet parts are made of SS304.

Applications

• Microbial & cell culture research

• Enzyme, vaccine & antibiotic production

• Probiotics & starter culture development

• Academic training & pilot studies

Controls:

• Automatic Temperature Control
• Aeration Control through rotameter/MFC
• Automatic Nutrient Feeding Control
• Automatic Exhaust Gas Pressure Monitoring & Control
• Automatic Agitation Control
• Automatic Vessel Sterilization Control
• Automatic Redox Monitoring & Control
• Automatic pH Control
• Automatic OD/Turbidity Measurement
• Automatic DO Control (Cascade Control)
• Automatic Back Pressure Monitoring
• Batch Recipe System
• Control Panel – Independent / Combined
• Mobile Application
• SMS Alert Facility
• Supervisory Control And Data Acquisition (SCADA)